What we DID test is that the within patient plasmid genetic distance is significantly different from the between plasmid genetic distance. Pointing to plasmid found within each patient not being randomly extracted from the dataset (hence probably spread by conjugation)

This was an amazing within UKHSA collaboration, with Fan and Leo, who are data scientists with a statistical background, doing an amazing job at learning and understanding bioinfomatics and plasmid epidemiology! Any feedback/questions really appreciated!