"Epigenetic control and inheritance of rDNA arrays" New preprint from the T2T acrocentrics team! We find a tight link between methylation and transcription of the rDNAs, including the occasional silencing of entire arrays www.biorxiv.org/content/10.1...
Martin Hunt has made Incremental release 2024-08 on AllTheBacteria - adds 507k assemblies taking us up to 2.44 million in total: github.com/AllTheBacter...allthebacteria.readthedocs.io/en/latest/in... 1/n
Out today in Nature Methods, our first attempt make personalized pangenomes: rdcu.be/dTD3ogithub.com/vgteam/vg), and many others.
Nature Methods - This work introduces a k-mer-based approach to customizing a pangenome reference, making it more relevant to a new sample of interest. This method enhances the accuracy of...
Glad you enjoyed it, Mo! Thanks for coming! ☀️
Next time! 🤞
T2T-F2F 2024 is a wrap! Great to hear about the new discoveries being enabled by complete genomes, and to meet so many new, enthusiastic T2T’ers. Thanks for the great meeting @khmiga.bsky.social@ucscgenomics.bsky.social !! 🎉
Finally on some samples we have all 46 human chromosomes T2T. Update to verkko 2.2, last big release of this summer! github.com/marbl/verkko
Telomere-to-telomere assembly of accurate long reads (PacBio HiFi, Oxford Nanopore Duplex, HERRO corrected Oxford Nanopore Simplex) and Oxford Nanopore ultra-long reads. - marbl/verkko
I'm hiring! Currently accepting applications for center coordinator, bioinformatics engineer/scientist, and postdoctoral researcher. Please share with those that might be interested: genomeinformatics.github.io/jobs2024/