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Ariel K. Frame
@arielframe.bsky.social
BSc Biology || PhD Neuroscience || Postdoc with Andrew Lin at University of Sheffield || Drosophila, aging, learning and memory, neurodegeneration bit.ly/ArielFrame_GoogleScholar - Header made with DALL-E
73 followers65 following18 posts
Reposted by Ariel K. Frame
CZcarlzimmer.bsky.social

The fruit fly brain has 140,000 neurons and nearly 500 feet of wiring. Here’s my story about how scientists have drawn its map—the first complete map of any complex adult brain. Gift link: nyti.ms/4gR4kx0 🧪

After a Decade, Scientists Unveil Fly Brain in Stunning Detail
After a Decade, Scientists Unveil Fly Brain in Stunning Detail

Scientists have mapped out how 140,000 neurons are wired in the brain of the fruit fly, Drosophila melanogaster.

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Reposted by Ariel K. Frame
DBdddavi.bsky.social

Hard to overstate how pleased I am that the FlyWire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved. #neurosciencewww.nature.com/immersive/d4...

The FlyWire connectome: neuronal wiring diagram of a complete fly brain
The FlyWire connectome: neuronal wiring diagram of a complete fly brain

Artificial intelligence and human expertise meet to generate a map of all the connections in the fly brain. The resource is already being used by experimentalists and theoreticians to further our unde...

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Reposted by Ariel K. Frame
SLluschnig.bsky.social
Reposted by Ariel K. Frame
Fflybase.bsky.social

There's a surprise update to the #GAL4etc#QuickSearch#SplitSystemCombination#SplitGAL4#hemidriver#FlyBaseSkeetorial

The FlyBase GAL4 etc QuickSearch tab. Only the 'Anatomy/Cell Type' field is filled, with the FlyBase Anatomy Controlled Vocabulary term 'alpha/beta surface Kenyon cell. The tab heading is boxed in purple.
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Reposted by Ariel K. Frame
Nneurofly2024.bsky.social

That was such a great Neurofly2024! Amazing science, outstanding talks, by plenary speakers and by talks selected from abstracts, buzzing vibrant poster sessions. Hey Organising Committee, go celebrate! And looking forward to Neurofly2026!

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Reposted by Ariel K. Frame
MAhansonmark.bsky.social

Got around to making a starter pack. Please let me know who I've missed (I'm sure it's a lot!). But hopefully a good way to bring folks together from a broad and welcoming community. Also looking forward to learning of all the folks I'm missing here on Bluesky! 🦋🪰🐞🐝🪳🦟🐜 go.bsky.app/4EuqSbc

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AKarielframe.bsky.social

I’m happy to announce, my second large paper from my PhD is now out in iScience! Cognition in ♂ and ♀ mice had interesting changes when we altered neuronal lactate metabolism. Check it out if you're interested in #lactate #brainmetabolism #aging #cognition #ANLS doi.org/10.1016/j.isci.2024.110342

Graphical Abstract for Altered neuronal lactate dehydrogenase A expression affects cognition in a sex- and age-dependent manner.

Highlights
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Altered neuronal Ldha expression elicits cognitive changes depending on sex and age

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Induced neuronal Ldha causes cognitive deficits in old mice

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Knockout of neuronal Ldha causes cognitive improvements in old mice

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Neuronal lactate production may help or hinder cognition depending on the context
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Reposted by Ariel K. Frame
ALandrewclin.bsky.social

Check out our new review about sensory coding in the fly mushroom body, with Moshe Parnas and Julia Manoim! learnmem.cshlp.org/content/31/5...

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AK
Ariel K. Frame
@arielframe.bsky.social
BSc Biology || PhD Neuroscience || Postdoc with Andrew Lin at University of Sheffield || Drosophila, aging, learning and memory, neurodegeneration bit.ly/ArielFrame_GoogleScholar - Header made with DALL-E
73 followers65 following18 posts