New preprint in collaboration with @asantoslopez.bsky.socialwww.biorxiv.org/content/10.1...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Do you enjoy mysterious population stochasticity, chaotic dynamics, and/or popgen? Then this preprint might be for you! Super excited to share a project that has been an exciting journey, and a fun blend of theory and experiment! www.biorxiv.org/content/10.1...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Grateful to have had the opportunity to write a Current Biology Dispatch on @joaoascensao.bsky.socialauthors.elsevier.com/a/1ifo63QW8S...www.cell.com/current-biol...
New perspective paper with the amazing @asanchezlab.bsky.social@javierdelafuente.bsky.socialwww.embopress.org/doi/full/10....
Almost a decade after proposing this experiment in a grant application, we have a preprint! A huge experiment by Philippe Piccardi with many helping hands to generate and analyze the data especially genomic & transcriptomic analysis by Eric Ulrich! www.biorxiv.org/content/10.1...
Guest blog from me on Dynamic Ecology, a guide for beginning grads on developing a reading habit and project ideas! Super grateful for reposts :)
Note from Meghan: This is a guest post by my colleague Gina Baucom on a topic that's sure to be of interest to lots of readers! *** I lead a graduate-level professional development seminar* where we r...
Our latest on phage-plasmids(PP) is out! Two main findings. PP recombine more with (other) plasmids and phages than the latter, thereby connecting them. PP can become just phages or plasmids, which may then transition to be conjugative. All the world’s an MGE! www.nature.com/articles/s41...
Happy to share the final version of our paper on recombination & gene flow in the human gut microbiome. Heroic effort by @zzzhiru.bsky.social getting it over the finish line (>40 SI figures!) If you're interested the interplay between recombination & selection in the gut, Zhiru is the one to ask!
Excited (and relieved!) to share that my 1st paper in grad school finally came out in PLOS Biology! We were motivated by a very basic question: how fast, really, do bacteria exchange DNA in the human gut? (1/n)
Recombination is a ubiquitous force in bacterial evolution, but its dynamics are poorly characterized in many natural populations. This study presents a metagenomic approach for quantifying the landsc...
Ever wonder if V. cholerae loses genetic diversity due to bottlenecks as it passes through the gut? We have a little preprint about that! The answer, based on sequencing 200 genomes from 10 patients’ vomit and stool, is: maybe a little but not much!
Diversity of Vibrio cholerae O1 through the human gastrointestinal tract during cholera https://www.biorxiv.org/content/10.1101/2024.02.08.579476v1
Vibrio cholerae O1 causes the diarrheal disease cholera, and the small intestine is the site of acti
My first post on Bluesky app to share the culmination of a 6+ year (!) collaboration with Eric Durand investigating the Bacteroidota T6SS membrane complex. Thanks to all co-authors www.nature.com/articles/s41...
The type VI secretion system (T6SS) of Gram-negative bacteria is typically anchored to the cell envelope through a membrane complex (MC), but Bacteroidota appear to lack genes encoding canonical MC co...