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CP
Chris Ponting
@cgatist.bsky.social
Disease genomics & molecular mechanisms; ME/cfs: decodeme.org.uk/portal/ @ Edinburgh University. Views - my own. He/him.
270 followers44 following6 posts
CPcgatist.bsky.social

No more does a cell need to be placed at a single location in expression space. Stator allows cells to be labelled with many biological states. Work with dream team: Abel Jansma, Yuelin Yao, Jareth Wolfe, Luigi Del Debbio, Sjoerd Beentjes & Ava Khamseh Please send feedback!

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CPcgatist.bsky.social

Stator finds: 👉Sub-phases of the cell cycle, 👉Future fate of mouse embryonic cells, 👉Rare cell sub-types & 👉Cycling transformed cells whose expression signatures are prognostic in cancer. Example: Medium spiny neurons (MSN) from Direct pathway, with intermediate maturity

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CPcgatist.bsky.social

Stator works by finding high-order gene expression dependencies in sparse #scRNA seq data. The method is data driven & comes with its own Shiny App. Finds up to n=7 gene dependencies of expression OR non-expression.

1
CP
Chris Ponting
@cgatist.bsky.social
Disease genomics & molecular mechanisms; ME/cfs: decodeme.org.uk/portal/ @ Edinburgh University. Views - my own. He/him.
270 followers44 following6 posts