Lovely to chat to Jennie Jacques about #MEcfs#DecodeMEt.co/bijeB3WQ2e
Two new chapters from my free online book in human genetics out this weekend! These complete Part 3 of the book, on human population structure and history: 3.3: Human prehistory [separate thread] 3.4: Ancient DNA: a genetic time capsule [this thread] web.stanford.edu/group/pritch...
Call for US RECOVER Initiative to include ME/CFS www.meresearch.org.uk/call-for-us-...#MECFS#LongCovid
🚨‼️Biggest ever blood based study of people with ME versus controls shows a clear signature of disease *not connected to activity levels* that relates largely to chronic inflammation, insulin resistance and the liver disease‼️ 🚨 By @cgatist.bsky.socialwww.medrxiv.org/content/10.1...
medRxiv - The Preprint Server for Health Sciences
No more does a cell need to be placed at a single location in expression space. Stator allows cells to be labelled with many biological states. Work with dream team: Abel Jansma, Yuelin Yao, Jareth Wolfe, Luigi Del Debbio, Sjoerd Beentjes & Ava Khamseh Please send feedback!
Stator finds: 👉Sub-phases of the cell cycle, 👉Future fate of mouse embryonic cells, 👉Rare cell sub-types & 👉Cycling transformed cells whose expression signatures are prognostic in cancer. Example: Medium spiny neurons (MSN) from Direct pathway, with intermediate maturity
NEW PAPER Know that clustering single cells in reduced dimensions is problematic? Want to identify cell subtypes or states *without* clustering? Then check out Stator which finely resolves states & subtypes even among apparently homogeneous cells 🧵 www.biorxiv.org/content/10.1...
In May 2023, the ME Association requested the latest mortality data from the Office for National Statistics (ONS) & discovered that between 2001 and 2021,150 deaths in England & Wales were partly or fully attributable to ME/ #CFSmeassociation.org.uk/2023/11/me-a...#MEcfs
Malnutrition is the most serious life-threatening complication in those with ME/CFS, especially in very severe cases.