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David Epstein
@davidnotdave.bsky.social
Literature major, then neuroscience Ph.D., then addiction researcher. Enough-knowledge-to-endanger-myself in social sciences and statistics. He/him. Views my own.
110 followers118 following20 posts
DEdavidnotdave.bsky.social

Does anyone know of a blinded study in which a liquid medication (probably somewhat bitter) was matched to liquid placebo with any reported detail about how the respective flavors were checked? Every paper I've found has seemed to say "trust us, they matched."

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DEdavidnotdave.bsky.social

Bonus difficulty: it's a controlled substance. We can't just sip it ourselves.

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LAlabasedow.bsky.social

So this is obviously an issue with trials using Ayahuasca (a psychedelic brew with a strong taste) and trying to do placebo control. Here are some studies trying to do this: www.cambridge.org/core/journal...www.ncbi.nlm.nih.gov/pmc/articles...www.frontiersin.org/journals/psy...

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David Epstein
@davidnotdave.bsky.social
Literature major, then neuroscience Ph.D., then addiction researcher. Enough-knowledge-to-endanger-myself in social sciences and statistics. He/him. Views my own.
110 followers118 following20 posts