Can AlphaFold3 predict bacterial transcription factor binding sites on DNA? I tried to devise a fair test. The results are quite impressive. My test: I chose LexA (favorite TF at the @ErillLab) from E. coli K-12, and I generated "randomized" binding sites from the PWM. First 1/

of all, from what I read from Supplementary 2.5.2, AF3 was trained on Jaspar, which doesn't contain motifs for bacterial transcription factors! Please let me know if I'm missing some way in which bacterial TF motifs may have been available to AF3. Secondly, by "randomized" 2/