#methane Preprint: Dr. @microbe_mack’s work on culturing, proofing methanogenic growth, and studying transcriptional activity of an Archaeoglobi, Ca. Methanoglobus hypatiae tinyurl.com/625rcy88 . The Archaeoglobi have been known as obligately sulfate reducers since their 1st
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Please share! I expect to hire 1-2 new grad students (+1 postdoc?) to start fall 2024 to work on novel methanogens in three (!) archaeal phyla. Culture based & in situ work in Yellowstone! Previous work: tinyurl.com/yry9pcn6tinyurl.com/mtusv3he & preprint coming 2morrow
Thanks to the NASA Exobiology program for funding. Co-authors are Dr. Zackary Jay and Anthony Kohtz. Congrats Mackenzie!
@microbe_mack named the archaeon M. hypatiae in honor of Hypatia of Alexandria , a renowned mathematician, astronomer, and philosopher of ancient Alexandria wikipedia.org/wiki/Hypatia who made significant contributions to our understanding of nature.
methanogenic Archaeoglobi in 36 geochemically diverse thermal features of @YellowstoneNPS, suggesting their potential involvement in methanogenesis in these extreme habitats.
Ca. M. hypatiae is represented by a 1.6 Mb MAG with an estimated completeness of 100% and represents up to 67% of cells in the culture according to quantitative FISH. By mining 16S rRNA and mcrA gene amplicon datasets generated by our lab, we demonstrate the presence of
fluorescence and electron microscopy, stable isotope tracing, metagenomics, and metatranscriptomics, we demonstrate that M. hypatiae lives by methylotrophic methanogenesis and converts different methylamine (but not methanol) to methane.
in methanogenic hot spring mesocosms. Building on our previous work (tinyurl.com/yry9pcn6), we cultured Ca. Methanoglobus hypatiae, a methanogen within Archaeoglobaceae from a hot spring in @YellowstoneNPS. Using a combination of targeted cultivation, growth experiments,
cultivation in 1987. However, omics-driven studies implicated some Archaeoglobi in methanogenesis and three 2023 studies showed that Archaeoglobi can be enriched (tinyurl.com/yry9pcn6tinyurl.com/y3nv7j4btinyurl.com/bdhk4msk)