Confused by Neutrophils in Cancer? Check out our latest review! www.cell.com/trends/cance...
Nice fresh review on immune repertoire analysis from @victorgreiff.bsky.social
The adaptive immune receptor repertoire (AIRR) drives adaptive immune responses, which could determine disease outcomes, infectious disease and cancer. Mhanna, Bashour et al. outline the approaches an...
On top of that it can be parallelized on multiple machines using dask. More performance upgrades are on the way. Thanks to Tobias Ganzenhuber and Felix Petschko for working on this!
We released scirpy v0.15 with a focus on performance improvements. "alignment" distance to find similar clonotypes is now 2-3x faster by default. Additionally there's an (approximate) "fastalignment" metric that is up to 20x faster. scirpy.scverse.org/en/latest/ch...
For anyone who is working with Personalis data: We made an R package that automates loading the data into a MultiAssayExperiment: github.com/Boehringer-I...
Read Personalis datasets into MultiAssayExperiment objects - GitHub - Boehringer-Ingelheim/Personalis-io: Read Personalis datasets into MultiAssayExperiment objects