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Mark Ungrin
@mark-ungrin.bsky.social
Parent. Interdisciplinary biomedical researcher. Hardline scientist. PhD (Medical Biophysics, Cellular & Molecular Biology). Faculty. New platforms and real-world impact, emphasis on scientific rigour, reproducibility and efficiency. Diverse interests.
201 followers67 following32 posts
MUmark-ungrin.bsky.social

An RCT tests only the latter, but all too often ambiguous language is used to imply that the results then say something general about the first two (and - perhaps not so coincidentally - extend the range of authority claimed by the speaker).

A picture of a commercial product that uses false perspective to make a fish caught by an angler seem much larger than it really is.
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MUmark-ungrin.bsky.social

This is the crucial limitation of RCTs for this category of problems - they are big, they are expensive, they answer only a small number of questions (very often only one) and if you don't see an effect, often can’t tell you why - a significant drawback vs mechanistic approaches.

A picture of a cat pushing a wineglass off a shelf to see if it will bounce, and then repeating the action.
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Profile banner
MU
Mark Ungrin
@mark-ungrin.bsky.social
Parent. Interdisciplinary biomedical researcher. Hardline scientist. PhD (Medical Biophysics, Cellular & Molecular Biology). Faculty. New platforms and real-world impact, emphasis on scientific rigour, reproducibility and efficiency. Diverse interests.
201 followers67 following32 posts