MJ
Matthew J Shepherd
@matthewjshepherd.bsky.social
Postdoc at the University of Manchester, with Prof. Mike Brockhurst. Understanding and predicting the evolution of antimicrobial resistance in clinical Pseudomonas 🔬🦠
267 followers260 following26 posts
Thrilled to share our new article now out in Nature Reviews Microbiology! We review how bacterial #AMR#antibiotic#MicroSkywww.nature.com/articles/s41...
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology
In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...
We summarise evidence for four prevailing mechanisms of AMR emergence within-patient: i) Spontaneous mutation, ii) Horizontal transfer (de novo mechanisms), iii) Selection of existing resistance, and iv) immigration of resistant lineages from elsewhere (ecological mechanisms) 2/7
Awesome 👏👏👏 Congratulations Matt!!!
MJ
Matthew J Shepherd
@matthewjshepherd.bsky.social
Postdoc at the University of Manchester, with Prof. Mike Brockhurst. Understanding and predicting the evolution of antimicrobial resistance in clinical Pseudomonas 🔬🦠
267 followers260 following26 posts