With Ryzen 7950x reaching 32 threads. A threadripper may not be needed for most, but maybe your new TimsTOF ultra will run through samples fast enough to need a threadripper.

I have not compared and don't have access to a threadripper. Though they use the same architecture, I assume IPC would be similar. The main advantage is an increased number of cores and a number of PCI lanes. The number of PCI lanes don't matter much, as we don't need them for multiple GPUs.

I use a Ryzen 2600x with a 1TB 960 Evo M.2 drive and 48 GB RAM. It finishes much faster than any of the more expensive Lab computers with Xeon processors. I keep the task manager open when running FragPipe, MQ and DIA-NN; CPU and disk speed are always limiting factors on all lab computers.

Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis www.mcponline.org/ar... --- #proteomics #prot-paper