I use a Ryzen 2600x with a 1TB 960 Evo M.2 drive and 48 GB RAM. It finishes much faster than any of the more expensive Lab computers with Xeon processors. I keep the task manager open when running FragPipe, MQ and DIA-NN; CPU and disk speed are always limiting factors on all lab computers.

Do you know how rayzen and threadripper compare. Rayzen tend to have faster single core speeds but fewer threads.