Do you know how rayzen and threadripper compare. Rayzen tend to have faster single core speeds but fewer threads.

With Ryzen 7950x reaching 32 threads. A threadripper may not be needed for most, but maybe your new TimsTOF ultra will run through samples fast enough to need a threadripper.

I have not compared and don't have access to a threadripper. Though they use the same architecture, I assume IPC would be similar. The main advantage is an increased number of cores and a number of PCI lanes. The number of PCI lanes don't matter much, as we don't need them for multiple GPUs.