🧬💻🧪 Tagging for lists
New preprint alert! EuPRI has everything: * New binding data (174 RBPs) * New motifs (34,000 RBPs) * New ML for inferring motifs from protein sequence (JPLE) * Evolution of RBP motifs across eukaryotes * 12 Plant RBPs assigned PTR function. Stay tuned for more www.biorxiv.org/content/10.1...
RNA-binding proteins (RBPs) are key regulators of gene expression. Here, we introduce EuPRI (Eukaryotic Protein-RNA Interactions) — a freely available resource of RNA motifs for 34,736 RBPs from 690 e...
This has been in preprint for almost two years. Do you have a sense of what's new in this latest version?
Wouldn't that be a better candidate for the Economics prize, for better or worth?
A cure for cancer, which will also work on, would go a long way towards solving world peace... in case Nobel is listening
I would like to thank the Nobel Prize committee for underlining the importance of my lab’s research. We use AI (Physics) to study post-transcriptional regulation (Medicine), in a large part by using protein language models (Chemistry) to predict RNA-binding protein targets.
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Seems like methods to compute gene-gene similarity (for co-expression networks) would be relevant. There's a lot of work on that, Matt Weirauch did his entire thesis on that topic, e.g., onlinelibrary.wiley.com/doi/epdf/10.... Probably need to update the assumptions about observation noise
This chapter contains sections titled: Introduction Background Construction of GCNs Integration of GCNs with Other Data Analysis of GCNs GCNs for the Study of Cancer Conclusions Refer
#alphafoldarxiv.org/abs/2408.16975paddlehelix.baidu.com
The AlphaFold series has transformed protein structure prediction with remarkable accuracy, often matching experimental methods. AlphaFold2, AlphaFold-Multimer, and the latest AlphaFold3 represent...