New preprint alert! EuPRI has everything: * New binding data (174 RBPs) * New motifs (34,000 RBPs) * New ML for inferring motifs from protein sequence (JPLE) * Evolution of RBP motifs across eukaryotes * 12 Plant RBPs assigned PTR function. Stay tuned for more www.biorxiv.org/content/10.1...
RNA-binding proteins (RBPs) are key regulators of gene expression. Here, we introduce EuPRI (Eukaryotic Protein-RNA Interactions) — a freely available resource of RNA motifs for 34,736 RBPs from 690 e...
Wouldn't that be a better candidate for the Economics prize, for better or worth?
I would like to thank the Nobel Prize committee for underlining the importance of my lab’s research. We use AI (Physics) to study post-transcriptional regulation (Medicine), in a large part by using protein language models (Chemistry) to predict RNA-binding protein targets.
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#alphafoldarxiv.org/abs/2408.16975paddlehelix.baidu.com
The AlphaFold series has transformed protein structure prediction with remarkable accuracy, often matching experimental methods. AlphaFold2, AlphaFold-Multimer, and the latest AlphaFold3 represent...
When an article says "some scientists think" then remember this: I, a scientist, once thought I could fit a whole orange in my mouth. I could, it turns out, get it in there, but I hadn't given sufficient thought to the reverse operation.
Very excited to present my lab’s new work on genomic deep learning at Kipoi Seminar next Wed (10 Jan 2024)! 8:30a - 9:30a Pacific Time 11:30a - 12:30p Eastern Time 5:30p - 6:30p Central European Time Register for zoom link: tum-conf.zoom.us/meeting/regist… Details of talk:
Fun collaboration with Nikki Case and colleagues; my contribution was to extend our Candescence software for host-pathogen interactions.🧬🖥️ journals.asm.org/doi/full/10....
SHOCKER: world’s most cited epidemiologist who publishes a hundred papers a year but has been subject to extensive criticism for shoddy work opines that we should use quantitative metrics rather than qualitative evaluation to assess researchers. I’m baffled as to why Plos Biology published this.
Using quantitative metrics to assess researchers is often seen as a poor choice compared with using qualitative assessments. In this Perspective, the authors argue in favor of using rigorous, field-ad...