When I plotted out my labs, I found the same thing. My GFR increased once I started taking the drug and it's still elevated since then. The exact mechanism is unknown. But there's a few hints. Our kidneys have glucagon receptors and we don't know their full purpose.
Studies are ongoing but some possible reasons include that retatrutide induces mild nutritional ketosis and that may be helping the kidneys, as it can used a fuel source and reduces renal inflammation. Really fascinating, cutting edge science 🤓🤓 www.ncbi.nlm.nih.gov/pmc/articles...
Ketone bodies have a negative image because of ketoacidosis, one of the acute and serious complications in diabetes. The negative image persists despite the fact that ketone bodies are physiologically...