thanks Paul, highly appreciated 🙏

a few great summaries of our work by colleagues and the press: - The Conversation (engl): shorturl.at/nQRY1shorturl.at/FM047shorturl.at/gqMR5

Gabriel has collated all data and analysis code for you here: data: doi.org/10.18112/ope...zenodo.org/doi/10.5281/...

4. Regions with higher energy demand are involved in complex cognition, like inhibitory and memory processing, or reading.

3. Higher energy demand is associated with slow, chemical signaling of neuromodulators, such as serotonin or dopamine (transcriptomics and molecular imaging data).

2. Up to 67% higher energetic costs in evolutionarily most expanded brain regions.

Brain Imaging Setup: We measured the glucose metabolism throughout the functional connectome of the human brain (replication in three datasets using simultaneous PET/MR imaging). 1. Energy demand linearly scales with the degree of functional connectivity in individual brains.

Short answer: It’s not the size of the brain that makes us human; but we spend excessive energy on slow, chemical signaling in evolutionarily expanded regions of the brain.

‚Science Advances‘ published our paper in which we asked: "Where does all the sugar go in the brain?" doi.org/10.1126/scia...#funding#neuroskyence