Lets face it, now that UKBioBank results get published in top journals, no one can criticize anything with more than a 20% response rate.
Does this mean we can all get on with our lives and safely ignore selection bias? Of course not! Different studies have different patterns and strengths of selection which could realistically result in waaaay more bias (eg, recruitment into UKBioBank: doi.org/10.1093/ije/...).
Genetic analysis challenges the idea that loneliness directly causes diseases 🔬🧬🧠 www.news-medical.net/news/2024091...#Loneliness#Genetics#PublicHealth#DiseaseRisk#MendelianRandomization#Health#MentalHealth#UKBiobank#HumanBehaviour
Research reveals that loneliness is linked to numerous diseases observationally, but genetic analysis shows it's likely a marker rather than a cause.
Genetic Architecture of Human #TelomereLength#UKbiobank#ClonalHematopoiesis#NatureGenetwww.nature.com/articles/s41...
How does anyone get away with this? It makes our #UKBioBank look scientific.
Beer and cider significantly raise gout risk for both sexes, but men are more affected 🍻📊⚕️ www.news-medical.net/news/2024090...#GoutPrevention#Alcohol#Health#Gout#Beer#Cider#UKBiobank#Health#Inflammatory#Arthritis#PublicHealth
Study found that increased consumption of certain alcoholic beverages, particularly beer and spirits, is linked to a higher risk of gout in men, while women show varying associations depending on alco...
#mecfs#metsyn#UKbiobank#medsky
🚨‼️Biggest ever blood based study of people with ME versus controls shows a clear signature of disease *not connected to activity levels* that relates largely to chronic inflammation, insulin resistance and the liver disease‼️ 🚨 By @cgatist.bsky.social www.medrxiv.org/content/10.1...
medRxiv - The Preprint Server for Health Sciences
Another sensible precaution when using UKBioBank. Not sure if the authors were aware of its social bias .
All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for underrepresented populations https://www.biorxiv.org/content/10.1101/2024.08.06.606846v1
Recent studies have demonstrated that polygenic risk scores (PRS) trained on multi-ancestry data can
AI reveals genetic links in aging, chronic diseases, and lifestyle factors across nine organ systems 🧬🧠🔬 www.news-medical.net/news/2024080...#AI#Genetics#Aging#ChronicDiseases#PrecisionMedicine#DrugRepurposing#OrganHealth#Biomedical#Multiorgan#UKBiobank@natureportfolio.bsky.social
Research uncovers how genetic factors influence the biological age of different organ systems, revealing their connections to lifestyle, chronic diseases, and potential therapeutic interventions.
COVID pandemic accelerated brain aging, especially in males and deprived groups 🧠📉🔬 www.news-medical.net/news/2024072...#BrainHealth#COVID19#Pandemic#Neuroimaging#CognitiveDecline#PublicHealth#HealthInequality#Sociodemographics#UKBiobank#Brain#Aging@medrxivpreprint.bsky.social
The COVID-19 pandemic accelerated brain aging, particularly in males and those from deprived backgrounds, with significant cognitive performance decline in infected individuals. This impact was observ...