"We experimentally evolved #Drosophila#Immunology#InnateImmunityacademic.oup.com/evolut/advan...
Abstract. Disease resistance (defined as the host capacity to limit systemic infection intensity) and disease tolerance (defined as the host capacity to li
'Our data indicate that BCG vaccination impacts both the gene expression and epigenetic profiles of HSPCs for at least 90 days and that these changes are predictive of corresponding functional changes in donor-matched PBMCs challenged with Candida albicans.' #Immunology#InnateImmunity
Although the Bacille-Calmette-Guérin (BCG) vaccine is used to prevent tuberculosis, it also offers protection against a diverse range of non-mycobacte…
My continued biological education #LiquidLiquidPhaseSeparation#InnateImmunity#MolecularCellwww.sciencedirect.com/science/arti...
'Transiently infected participants have a robust (IFN-I) response in the nasal mucosal tissue shortly after viral exposure (...) By contrast, participants who had sustained infection showed delayed (...) mucosal IFN-I responses' #Covid#Covid19#Immunology#Virology#InnateImmunity
Controlled infection with SARS-CoV-2 of people who hadn’t previously been exposed to the virus reveals how molecular and cellular signatures of the immune response portend effective defence against CO...
What makes kids so remarkably resilient to acute #COVID19#SARSCoV2#innateimmunity#childrenwww.embopress.org/doi/full/10.... 🧵1/2
Everyone interested in cell-intrinsic antiviral #immunity, read this pre-print and the thread by its first author @nandangokhale from the lab of Savan Ram @UW_Immunology (you can literally feel his passion 😉) ⬇️ #RIGI #MAVS #RNA #viruses #antiviralresponse #innateimmunity #IFN
This study highlight the role of ORF6 in antagonizing #innateimmunity www.sciencedirect.com/topics/immun...www.sciencedirect.com/science/arti...
🟢 New review by Ph.D. student Saby Mathavarajah, hot off the press @ Biochemistry and Cell Biology. "LINE-1: an emerging initiator of cGAS-STING signalling and inflammation that is dysregulated in disease." #Transposons #Evolution #InnateImmunity tinyurl.com/y37kzmme
'The elucidation of the lipid metabolic pathways that promote innate immune memory contributes to our understanding of trained immunity and may help identify therapeutic tools and targets for the modulation of innate immune responses.' #immunology #InnateImmunity #Preprint
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