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Caiti Smukowski Heil
@caitismuheil.bsky.social
Evolutionary geneticist studying recombination, hybridization, and domestication in yeast! Asst. Professor at NC State 🔬🧬🍞 👦👦🐈🐈 she/her
132 followers136 following8 posts
CScaitismuheil.bsky.social

We speculate that the decreased crossover and shuffling helps facilitate the purging of introgression in the early generations following hybridization. Eager to hear others thoughts!

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CScaitismuheil.bsky.social

We employ the tool r bar (pubmed.ncbi.nlm.nih.gov/30635424/) to measure the amount of allele shuffling, and find that the decrease in crossovers in introgression translates to decreased shuffling on many chromosomes with introgression.

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CScaitismuheil.bsky.social

We find that heterozygous introgression significantly changes the recombination landscape. Crossovers are decreased and non-crossovers are increased in regions of heterozygous introgression (similar to what is seen in heterozygous inversions!)

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CScaitismuheil.bsky.social

Recombination plays an important role in the distribution of introgression in the generations following hybridization in lots of species 🦋🌽🐟👩‍🔬 We use the awesome power of yeast to WGS the meiotic products of two crosses, one with introgression and one without, and call crossovers and non-crossovers

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CScaitismuheil.bsky.social

www.heillab.com Thanks!!!

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Profile banner
CS
Caiti Smukowski Heil
@caitismuheil.bsky.social
Evolutionary geneticist studying recombination, hybridization, and domestication in yeast! Asst. Professor at NC State 🔬🧬🍞 👦👦🐈🐈 she/her
132 followers136 following8 posts