Red Queen longevity "Specifically, retrotransposon activity may have led to the expansion of DNA repair- associated retrogenes, which, in turn, allowed for the tolerance of higher retrotransposon activity." #Preprintwww.biorxiv.org/content/10.1...
Great highlight of the Cellerino and Hoffman (FLI) labs on sequencing of the longest lived vertebrate. 👏 Lots and lots of transposable elements... The piece also remarks their most important (and underestimated) trait: they start reproducing at 140yo! 😳 www.nytimes.com/2024/09/22/s...
Scientists have mapped the genome of the Greenland shark, which could offer clues to the animal’s extreme longevity.
"While previous studies have reported that DNAm age is not related to #telomere#agingwww.nature.com/articles/s41...
A proteomic aging clock, developed using data from the UK Biobank and validated using data from the China Kadoorie Biobank and FinnGen, predicts the incidence of 18 major chronic diseases, as well as ...
I don’t know who needs to hear this, but sharks absolutely get cancer. Even if sharks didn’t get cancer, eating shark wouldn’t cure your cancer any more than eating LeBron James would make you better at basketball. (Images of shark tumors from Andrew Fox, via a NBC News article)
Thank you, France 🇫🇷, for protecting the Portuguese (including my family) exiled in your country and celebrating with us our Liberty Day ✊. #25deAbrilSemprewww.youtube.com/watch?v=evKM...
Pour suivre la Présidence de la République :Facebook : https://www.facebook.com/elysee.frTwitter : https://twitter.com/elyseeInstagram : https://www.instagra...
50 years have passed from the carnation revolution that brought liberty, the end to an unjust war and democracy. This song is from one of the major poets in the Portuguese language. #25deAbrilSempre Translation and context follow the link below:lyricalbrazil.com/2012/04/25/tanto-mar/
Enter a new world in telomere biology: “The same rank order was found in newborn cord blood, suggesting that telomere length is determined at birth and chromosome end–specific telomere length differences are maintained as telomeres shorten with age.” www.science.org/doi/10.1126/...
Short telomeres cause age-related disease and long telomeres predispose to cancer; however, the mechanisms regulating telomere length are unclear. We developed a nanopore-based method, Telomere Profil...
Very saddened to learn that Judith Campisi has died. We had a wonderful conversation for an IGC podcast that was never released - she was a guest of @miguelgf.bsky.social Dr Campisi was a blast, I hope the recording still exists somewhere.
An inspirational pioneer and leader in the field of cellular senescence.
cGAS-STING and IFNs are responsible for aging of #telomerase#zebrafish🐟#telomeres#cGAS-STING#lifespan#cancer#preprintwww.biorxiv.org/content/10.1...
Here we discuss how #telomere#epigenetic#telomerase#parents#life#cellularjournals.biologists.com/dmm/article/...
Summary: Telomere length can be considered an epigenetic trait that depends on the genetic telomerase status as well as on inherited progenitor telomere length. This can impact human disease for gener...