The Nobel Prize in physiology or medicine was awarded to Victor Ambros and Gary Ruvkun. The prize was awarded for the discovery of microRNA and “its role in post-transcriptional gene regulation.” MicroRNA plays an important role in gene regulation and how organisms develop and function.

Nobel Prize in physiology or medicine awarded to Victor Ambros and Gary Ruvkun

The prize was awarded for the discovery of microRNA and “its role in post-transcriptional gene regulation.” MicroRNA plays an important role in gene regulation and how organisms develop and function.

🎉You asked & we listened... @discovimmunol.bsky.social#VeterinaryImmunology#researchbit.ly/4ddaZ1K

Delighted to share our work developing an mRNA vaccine for C. difficile. This study with Drew Weissman’s lab was co-led by two truly amazing scientists: Alexa Semon from the Zackular lab and Mohamad-Gabriel Alameh from CHOP (formerly Weissman lab)! www.science.org/doi/10.1126/...

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine targeti...

It's been a while since I wrote a full blog article. I find the greatest writing motivation from being mad about stuff. I tried tackling the issue of bullying in academia. It started as a rant, but I tried my best to make it something useful for others. Feedback VERY welcome. #AcademicSky#PhDSky

“I Don’t Want to Cause Trouble”: Acceptance of Bullying in Academia

Author: Erin Pallott // Editors: Luke Marshall, Sophie Alshukri When I joined my PhD programme, I needed to figure out which lab I wanted to join. I got given lots of advice on what to ask other Ph…

Very cool new paper suggesting that #helminths#inflammation#neuron#myeloid#IL-33#ImmunoSkywww.nature.com/articles/s41...

MrgprA3 neurons drive cutaneous immunity against helminths through selective control of myeloid-derived IL-33 - Nature Immunology

Herbert and colleagues show MrgprA3+ neurons activate myeloid cells to promote cutaneous IL-17-dependent immunity against Schistosoma mansoni.

paraCell: A novel software tool for the interactive analysis and visualization of host-parasite single cell RNA-Seq data (without knowing programming) https://biorxiv.org/content/10.1101/2024.08.29.610375v1http://cellatlas.mvls.gla.ac.uk#scRNAseq#parasites

2024 has been a fantastic year of lung/imm/mac papers with some critical insights on host/pathogenesis. I'm highlighting some papers that I found in this thread, perhaps we can build more immune niches on sky app with help of @rodrahimi.bsky.social who initiated discovery imm stack. 🧵 x/n. Let's go.

Interesting new paper from @annaandrusaite.bsky.social#microbiota#butyrate#cDC#ImmunoSkywww.mucosalimmunology.org/article/S193...

www.nature.com/articles/s41...#immunosky IL-4 ♥️ but what’s it doing to TAMs?

The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer - Nature

Fc–IL-4, a typical type 2 cytokine, reinvigorates exhausted CD8+ T cells in tumours, underscoring this fusion protein as a potent immunotherapy that synergizes effectively with type 1 immunity against...

🎉Today is LSHTM's birthday! We're celebrating 125 years as one of the world's leading #publichealthbit.ly/4dspvCS

Origins of LSHTM on our 125th Birthday - Library, Archive & Open Research Services blog

125 years ago today, on 2nd October 1899, the School opened its doors to its first...